Kenneth Pettine can be considered the ‘godfather’ of mesenchymal stem cell therapy. He coined the term, “Friends don’t let friends get fused.”

“I’m convinced your body wants to heal itself,” said Kenneth Pettine (retired). “The problem in orthopedics and spine is there’s a paucity of blood supply to the joints or the disc in your back. If you injure your cartilage or disc, it has very little capacity to heal itself.”Becker Spine. 

The article goes on to state that the key to regenerative medicine in orthopedics and spine is in the mesenchymal stem cell.  The reason is that it has the ability to differentiate into osteoblasts, chondroblasts or fibroblasts.

“This may be the most important stem cell in your body,” Dr. Pettine (retired) explained. “The MSC is the cell that modulates your immune system through its paracrine ability to release numerous growth factors, cytokines, chemokines, and inhibitors…It’s the conductor and your body is the orchestra.”

Throughout his career, Kenneth Pettine has served as principal investigator for 15 FDA IDE studies focused on non-fusion technology.

Mr. Kenneth Pettine (retired) offers advice and insight on his new website,

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